User:Herb5902/Milk Thistle

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Silybum marianum

silybin
  • Bones
  • Diabetes
    • improves insulin sensitivity
  • Silymarine + NAC inhibits TNF-α, IL-1β, IL-6 levels.
  • Kidney function
    • The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury
    • increases creatinine clearance
    • reduces proteinuria
    • improves kidney functions
    • protects against renal injury through:
      • normalization of lipid metabolism and
      • mitochondrial biogenesis
  • Antimicrobial

Adverse effects:

  • gas

Kidneys and diabetes

Milk Thistle protects against renal injury through normalization of lipid metabolism and stimulation of mitochondrial biogenesis. It prevents glucose induced podocyte injury, increases creatinine clearance, and reduces proteinuria. Milk thistle also improves insulin sensitivity.