User:Herb5902/Goldenseal

Hydrastis canadensis

alkaloids 
* berberine, 
* canadine, and 
* canadaline

• diarrhea
• cyclooxygenase-2 (COX2) inhibitor
• Berberine exerts renoprotective effects through its anti-oxidant, anti-inflammatory, and anti-apoptotic properties.
• Blood Sugar
  • increased insulin
    • sensitivity
      • TNF-α and IL-6 are important mediators of insulin resistance
        • induce serine phosphorylation of insulin receptor substrate (IRS)
    • secretion
      • TNF-α and IL-6 cause islet dysfunction and accelerate the progression of diabetes
  • stimulates energy-dissipation via brown adipose tissue (BAT) activation
• Antimicrobial
  • antiviral,
    • influenza,
    • herpes simplex
  • antibacterial,
    • Staphylococcus
    • Strep
  • antifungal
    • Candida albicans, and
    • Aspergillus fumigatus,
  • antiparasitic
    • protozoan parasites
      • Giardia lamblia
      • Blastocystis hominis
• anti-carcinogenic