User:Herb5902/Ashwagandha root

Withania somnifera

withaferin A (WA) 

Benefits:

• Neuroprotective and
• anti-inflammatory
  • interleukin-10 (IL-10) inhibitor
  • Together with giloy ghanvati (Tinospora cordifolia), swasari ras (a traditional herbo-mineral formulation), and tulsi ghanvati (Ocimum sanctum), Aswagandha root reduces CRP, IL-6, and TNF-α.
• Oxidative stress
• Diabetes
  • withaferin A (WA) reduces serum insulin levels
  • reduces succinate dehydrogenase activity in the mitochondria
  • Improves mitochondrial function
  • enhances mitochondrial activity in brown fat and skeletal muscle
  • increases mitochondrial uncoupling protein 1 (UCP1) expression in the mitochondria
• Arthritis
• Blood pressure
• Alzheimer’s
• Cancer
• Athletic performance and sleep
• Infertility

Adverse Effects:

• Bleeding
• Allergies
• Prostate cancer
• Autoimmune or thyroid disorder
• Drowsiness
• Diarrhea