Urolithin A powder
Contents
Description
Urolithin A powder Urolithins are secondary metabolites of ellagic acid derived from ellagitannins. In humans ellagitannins are converted by the gut microflora into ellagic acid which is further transformed into urolithins A, urolithin B, urolithin C and urolithin D in the large intestines.[1]
Urolithin A (UA) is the most prevalent metabolite of ellagitannins. However, urolithin A is not known to occur naturally in any dietary sources.[2]
Urolithin B (UB) is an abundant metabolite produced in the gut through transformation of ellagitannins. Urolithin B is the last product after all the other urolithin derivatives are catabolized. Urolithin B is found in urine as urolithin B glucuronide.[3]
Urolithin A 8-Methyl Ether is the intermediate product during the synthesis of Urolithin A. It is a significant secondary metabolite of ellagitannin and possess antioxidant and anti-inflammatory properties.[4]
Manufacturers
Cofttek is the best Urolithin A powder manufacturer in China. Our factory has a complete production management system (ISO9001 & ISO14001), with a monthly production capacity of 400kg. [5]
Where to buy?
cofttek is Urolithin A Powder best wholesaler manufacturer [6] [7]
Urolithin A powder Specifications
- Name: Urolithin A
- Chemical Name: 3,8-Dihydroxybenzo[c]chromen-6-one
- CAS: 1143-70-0
- Chemical Formula: C13H8O4
- Molecular Weight: 228.2
- Color: White to off-white solid powder
- InChi Key: RIUPLDUFZCXCHM-UHFFFAOYSA-N
- SMILES Code: O=C1C2=CC(O)=CC=C2C3=C(O1)C=C(O)C=C3
- Function: Urolithin A, a gut-microbial metabolite of ellagic acid, exerts anti-inflammatory, antiproliferative, and antioxidant properties. Urolithin A induces autophagy and apoptosis, suppresses cell cycle progression, and inhibits *DNA synthesis.
- Application: Urolithin A is a metabolite of ellagitannin; Pharmaceutical Intermediates
- Solubility: Soluble in DMSO (3 mg/mL).
- Storage Temp: Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years).
- Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Reviews
References
- ↑ https://www.cofttek.com/product/urolithin-a/
- ↑ https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2788244
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679724/
- ↑ https://en.wikipedia.org/wiki/Urolithin_A
- ↑ https://www.cofttek.com/products/urolithin/
- ↑ https://www.nature.com/articles/s41430-021-00950-1
- ↑ https://en.wikialpha.org/wiki/Cofttek
