User:Herb5902/r+ alpha lipoic acid

Benefits:

• HIV reverse transcriptase inhibitor
• α-lipoic acid induces apoptosis in human colon cancer cells
• Activates AMPK
• Reduces insulin resistance
• Modulates Nrf2 transcription.
• Suppresses renal oxidative stress and inflammation.
• Enhances sirtuin 1 deacetylase activity
• increases adipose triacylglycerol lipase expression
• decreases fatty acid synthase abundance
• Prevents renal tubular cell apoptosis, fibrosis, and diabetic nephropathy
• Adults can take up to 2,400 mg without harmful side effects
• Improves Intestinal Dysmotility (does it cause diarrhea?)
• Colitis
• Streptococcus

Side effects:

• Hepatotoxic
• Flatulence

Diabetic nephropathy

In addition to activating AMPK and reducing insulin resistance, alpha lipoic acid modulates Nrf2 transcription, suppresses renal oxidative stress, reduces inflammation, enhances sirtuin 1 deacetylase activity, increases adipose triacylglycerol lipase expression, and decreases fatty acid synthase abundance. It also prevents renal tubular cell apoptosis, fibrosis, and diabetic nephropathy.