A. S. M. Muhtasim Fuad Sohan
A. S. M. Muhtasim Fuad Sohan was born in Bogura, Bangladesh. He Studied his Bachelor in Engineering from Yangzhou University. He have the necessary skills to fabricate, design, and simulate experimental conditions of a microfluidic chip. He can use different CAD software such as SolidWorks, CATIA, Fusion 360, AutoCad. Besides this, He is familiar with rendering software like Blender. The accumulated experience of his with COMSOL Multiphysics and ANSYS for Finite Elements Analysis helps to perform efficient simulations.
A. S. M. Muhtasim Fuad Sohan has also helped with volunteer work in Yangzhou International Horticultural Expositions. He is also an academic scholar. Moreover, he plans to start his own lab someday. He said, “In my short research career, I've learned how to work in a research group, cope with challenges, and contribute to a project—working with a research group that focuses on multidisciplinary research has taught me how to learn as well as the devotion required to make it happen."
He joined Associate Professor Dr Binfeng Yin's lab. In this research group, his first project involves designing a Snail-shaped microfluidic chip (SMC) with high sensitivity and low detection time for the multiplex detection of cTnI, CK-MB, and Myo. The SMC comprises three layers: a channel layer containing a mixer and reaction zone, a reaction layer coated with capture antibodies, and a base layer. As a signal readout, the chemiluminescence approach was used. SMC detected cTnI, CK-MB, and Myo at concentrations as low as 1.02, 1.37, and 4.15, respectively.
Another project is investigating the mixing performance of three passive micromixers with varying mathematical spiral shapes. We used numerical simulation and visualization studies to investigate the fluid flow properties of Archimedes spiral, Fermat spiral, and hyperbolic spiral constructions with varying channel widths and Reynolds numbers (Re) ranging from 0 to 10. Furthermore, to put our research to the test, we incorporated a Fermat spiral channel onto a microfluidic device to detect an acute myocardial infarction (AMI) marker.
Furthermore his third experience in developing an enzyme method-based microfluidic that can detect Cu2+ in seawater quickly. Cu2+ is converted to Cu+ in this study to limit horseradish peroxidase (HRP) activity. The chip supports both naked eye and spectrophotometer modes of operation. Cu2+ concentrations follow a perfect linear relationship, with absorbance values ranging from 3.91 nM to 256 M. Cu2+ is detected by the suggested enzyme method-based microfluidic device with a limit of detection (LOD) of 0.87 nM. Furthermore, the chip realizes the functions of two AND gates in series.
1. Yin B, Wan X, Qian C, Sohan A, Wang S and Zhou T (2021) Point-of-Care Testing for Multiple Cardiac Markers Based on a Snail-Shaped Microfluidic Chip. Front. Chem. 9:741058. doi: 10.3389/fchem.2021.741058
2. Yin B, Yue W, Sohan A, Zhou T, Qian C, Wan X (2021) Micromixer with fine-tuned mathematical spiral structures. ACS Omega. doi:10.1021/acsomega.1c05024
3. Yin B, Wan X, Qian C, Sohan A, Zhou T, Yue W (2021) Enzyme Method-Based Microfluidic Chip for the Rapid Detection of Copper Ions. Micromechanics. doi: 10.3390/mi12111380